Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27839480 | 0.80 | USP2 (0.61) | CA1CA2CA9CA12CA4 | |
| SCHEMBL13729928 | 0.80 | NAMPT (0.50) | CA1CA2CA9CA12CA4 | |
| SCHEMBL159152 | 0.80 | HSD11B1 (0.61) | CA1CA2CA9CA12CA4 | |
| SCHEMBL6302757 | 0.77 | USP2 (0.68) | MAPTSMN1; SMN2USP2ALDH1A1MEN1 | |
| SCHEMBL18498824 | 0.77 | ALDH1A1 (0.49) | TDO2ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL18498840 | 0.77 | ALDH1A1 (0.49) | TDO2ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL159900 | 0.76 | SMYD3 (0.45) | CA1CA2CA9CA12CA4 | |
| SCHEMBL5018821 | 0.76 | USP2 (0.71) | SMN1; SMN2USP2ALDH1A1MEN1POLB | |
| SCHEMBL25231648 | 0.73 | NAMPT (0.46) | SMN1; SMN2USP2ALDH1A1MEN1POLB | |
| SCHEMBL15231957 | 0.73 | POLB (0.67) | SMN1; SMN2KDM4EUSP2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080124807-A1 | Protein tagging reagents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-05-29 | — | — | US | disclosed |
| US-20080124807-A1 | Protein tagging reagents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-05-29 | — | — | US | disclosed |
| US-20080124807-A1 | Protein tagging reagents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124807-A1 | Protein tagging reagents | TH, TPH1, TPH2 | CA1 4702/4885CA2 4674/4885CA9 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.