Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034245 | 0.90 | CSNK2A1 (0.43) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL1984241 | 0.89 | CYP1A2 (0.52) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL5032298 | 0.82 | LMNA (0.43) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL8220033 | 0.80 | ALDH1A1 (0.44) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL8223215 | 0.79 | CYP1A2 (0.47) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL8224344 | 0.78 | ALDH1A1 (0.43) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL1236256 | 0.78 | CYP1A2 (0.56) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL30957371 | 0.78 | ESR1 (0.49) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL1837743 | 0.78 | ESR1 (0.49) | LMNAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL28589559 | 0.78 | CYP1A2 (0.60) | LMNAKDM4EMAPTNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |