SCHEMBL5032298

SCHEMBL5032298

CCCCOc1ccc([SiH3])c(OCCCC)c1OCCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ MCHR1 Q99705 1/20 0.38
▸ TDP1 Q9NUW8 2/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ GLA P06280 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ CHRM2 P08172 2/20 0.37
▸ CHRM1 P11229 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ ACHE P22303 1/20 0.37
▸ KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5373491 0.94 MCHR1 (0.40) LMNAALDH1A1KDM4EMAPTNPSR1
SCHEMBL2686471 0.90 ALDH1A1 (0.42) LMNAALDH1A1KDM4EMAPTNPSR1
SCHEMBL1984241 0.88 CYP1A2 (0.52) LMNAALDH1A1KDM4EMAPTNPSR1
SCHEMBL29091824 0.85 CYP1A2 (0.52) LMNAALDH1A1KDM4EMAPTNPSR1
SCHEMBL5034227 0.82 LMNA (0.44) LMNAALDH1A1KDM4EMAPTNPSR1
SCHEMBL9420344 0.81 SMN1; SMN2 (0.34) LMNAKDM4EMAPTTDP1L3MBTL1
SCHEMBL8220033 0.78 ALDH1A1 (0.44) LMNAALDH1A1KDM4EMAPTNPSR1
SCHEMBL158540 0.78 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTNPSR1L3MBTL1
SCHEMBL8223215 0.78 CYP1A2 (0.47) LMNAALDH1A1KDM4EMAPTNPSR1
SCHEMBL30957371 0.77 ESR1 (0.49) LMNAALDH1A1KDM4EMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7186782-B2 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2007-03-06 — — US claimed
US-20060041079-A1 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION 2006-02-23 — — US claimed
US-20230087596-A1 ESTER COMPOUND, METHOD FOR PRODUCING SAME, POLYMER, THERMOSETTING RESIN COMPOSITION AND CURED FILM KYOEISHA CHEMICAL CO., LTD. (JP) 2023-03-23 — — US disclosed
EP-4067395-A1 ESTER COMPOUND, METHOD FOR PRODUCING SAME, POLYMER, THERMOSETTING RESIN COMPOSITION AND CURED FILM Kyoeisha Chemical Co., Ltd. (JP) 2022-10-05 — — EP disclosed
CN-114829415-A Ester compound, method for producing same, polymer, thermosetting resin composition, and cured film 共荣社化学株式会社 2022-07-29 — — CN disclosed
WO-2021132251-A1 ESTER COMPOUND, METHOD FOR PRODUCING SAME, POLYMER, THERMOSETTING RESIN COMPOSITION AND CURED FILM 共栄社化学株式会社 2021-07-01 — — WO disclosed
WO-2021131030-A1 ESTER COMPOUND, PRODUCTION METHOD THEREFOR, POLYMER, THERMALLY CURABLE RESIN COMPOSITION, AND CURED FILM 共栄社化学株式会社 2021-07-01 — — WO disclosed
US-7466893-B2 Curable resin composition for light guide formation, curable dry film for light guide formation, cured resin and light guide KANSAI PAINT CO., LTD. (JP) 2008-12-16 — — US disclosed
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 — — EP disclosed
US-20080226245-A1 Epoxy resin that is modified with a tetraalkoxysilane or alkyltrialkoxysilane to form a hydrolyzable resin and another resin that is reactive with an epoxy group, such as an acrylic acid-acrylate copolymer; optical waveguides with high heat resistance, excellent mechanical strength and transparency KANSAI PAINT CO., LTD. (JP) 2008-09-18 — — US disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 — — WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 — — US disclosed
US-7186782-B2 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2007-03-06 — — US disclosed
US-20060041079-A1 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION 2006-02-23 — — US disclosed
US-5731037-A CONTROLLING SURFACE MOISTURE OF BUILDING MATERIAL KANSAI PAINT CO., LTD. (JP) 1998-03-24 — — US disclosed
EP-0236674-B1 Improved mineral filled rubber composites DOW CORNING (US) 1994-02-16 — — EP disclosed
US-4965312-A Nonaqueous vehicle composition for coating materials KANSAI PAINT COMPANY, LIMITED (JP) 1990-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230087596-A1 ESTER COMPOUND, METHOD FOR PRODUCING SAME, POLYMER, THERMOSETTING RESIN COMPOSITION AND CURED FILM RER1, EMG1, SETDB1 LMNA 2861/4885ALDH1A1 1084/4885KDM4E 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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