Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8224344 | 0.98 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL8227403 | 0.92 | L3MBTL1 (0.43) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL8223215 | 0.92 | CYP1A2 (0.47) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL1984241 | 0.89 | CYP1A2 (0.52) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL8225071 | 0.86 | L3MBTL1 (0.47) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL5034227 | 0.80 | LMNA (0.44) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL24661358 | 0.79 | CYP1A2 (0.47) | ALDH1A1KDM4EMAPTCYP1A2CYP2C9 | |
| SCHEMBL8216828 | 0.79 | CYP1A2 (0.38) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL5032298 | 0.78 | LMNA (0.43) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL30957371 | 0.78 | ESR1 (0.49) | ALDH1A1KDM4ELMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140274-A | Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-31 | — | — | US | disclosed |