SCHEMBL5035140

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5034701	0.95	HSD11B1 (0.41)	HSD11B1TRPC3TRPC6LRRK2NPC1
	SCHEMBL5035129	0.91	TRPC3 (0.40)	TRPC3TRPC6LRRK2NPC1RAB9A
	SCHEMBL5034736	0.90	HSD11B1 (0.45)	HSD11B1TRPC3TRPC6NPC1RAB9A
	SCHEMBL5032609	0.89	DPP4 (0.43)	HSD11B1NPC1RAB9ASCDHCRTR1
	SCHEMBL5032615	0.89	DPP4 (0.43)	HSD11B1NPC1RAB9ASCDHCRTR1
	SCHEMBL5032560	0.88	HSD11B1 (0.49)	HSD11B1TRPC3TRPC6NPC1RAB9A
	SCHEMBL5032648	0.88	ALDH1A1 (0.48)	TRPC3TRPC6NPC1RAB9AHPGD
	SCHEMBL5035125	0.87	KMT2A (0.43)	NPC1RAB9AHPGDSMN1; SMN2ALDH1A1
	SCHEMBL5032473	0.86	RAB9A (0.42)	NPC1RAB9AALDH1A1LMNAKDM4E
	SCHEMBL5032544	0.86	HTR2C (0.42)	TRPC3TRPC6LRRK2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.