SCHEMBL5034848

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5034720	0.90	HSD11B1 (0.46)	HSD11B1SMN1; SMN2GRM5ALDH1A1POLB
	SCHEMBL5034737	0.89	DPP4 (0.43)	GRM5
	SCHEMBL5034739	0.89	DPP4 (0.43)	GRM5
	SCHEMBL14190191	0.89	DPP4 (0.43)	GRM5
	SCHEMBL5035256	0.88	KMT2A (0.41)	MEN1KMT2AGRM5ALDH1A1HPGD
	SCHEMBL5034894	0.87	RAB9A (0.40)	MEN1KMT2AALDH1A1NPC1RAB9A
	SCHEMBL5032584	0.86	HCRTR1 (0.41)	HSD11B1LRRK2SMN1; SMN2ALDH1A1HCRTR1
	SCHEMBL5035140	0.85	HSD11B1 (0.41)	HSD11B1LRRK2SMN1; SMN2ALDH1A1HCRTR1
	SCHEMBL5036600	0.84	HPGD (0.43)	LRRK2MEN1KMT2ASMN1; SMN2POLB
	SCHEMBL5035234	0.83	ALDH1A1 (0.41)	MEN1KMT2AALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.