Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035826 | 1.00 | ALDH1A1 (0.47) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL5399646 | 0.92 | MMP12 (0.44) | ALDH1A1RECQLTHRBTAAR1 | |
| SCHEMBL7617220 | 0.92 | ALDH1A1 (0.43) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL7622507 | 0.92 | ALDH1A1 (0.45) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL8499772 | 0.89 | ALDH1A1 (0.43) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL8499575 | 0.89 | ALDH1A1 (0.43) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL8496246 | 0.89 | ALDH1A1 (0.43) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL8500326 | 0.89 | FFAR1 (0.50) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7713882 | 0.87 | ALDH1A1 (0.46) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL19592164 | 0.87 | S1PR1 (0.39) | ALDH1A1RECQLTHRBTAAR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594508-A4 | NOVEL BICYCLIC COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-12-31 | — | — | EP | disclosed |
| EP-1594508-A2 | NOVEL BICYCLIC COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004071442-A2 | NOVEL BICYCLIC COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-08-26 | — | — | WO | disclosed |