Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035787 | 1.00 | ALDH1A1 (0.47) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL5399646 | 0.92 | MMP12 (0.44) | ALDH1A1RECQLTHRBTAAR1 | |
| SCHEMBL7617220 | 0.92 | ALDH1A1 (0.43) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL7622507 | 0.92 | ALDH1A1 (0.45) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL8499772 | 0.89 | ALDH1A1 (0.43) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL8499575 | 0.89 | ALDH1A1 (0.43) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL8496246 | 0.89 | ALDH1A1 (0.43) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL8500326 | 0.89 | FFAR1 (0.50) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7713882 | 0.87 | ALDH1A1 (0.46) | ALDH1A1RECQLTHRBTAAR1NPC1 | |
| SCHEMBL19592164 | 0.87 | S1PR1 (0.39) | ALDH1A1RECQLTHRBTAAR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | SHIVALIK RASAYAN LIMITED (IN) | 2022-05-19 | — | — | US | claimed |
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2015-12-03 | — | — | US | claimed |
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | SHIVALIK RASAYAN LIMITED (IN) | 2022-05-19 | — | — | US | disclosed |
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | SHIVALIK RASAYAN LIMITED (IN) | 2022-05-19 | — | — | US | disclosed |
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | SHIVALIK RASAYAN LIMITED (IN) | 2022-05-19 | — | — | US | disclosed |
| US-9732030-B2 | Process for the preparation of fingolimod and its salts | SHILPA MEDICARE LIMITED (IN) | 2017-08-15 | — | — | US | disclosed |
| US-9732030-B2 | Process for the preparation of fingolimod and its salts | SHILPA MEDICARE LIMITED (IN) | 2017-08-15 | — | — | US | disclosed |
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2015-12-03 | — | — | US | disclosed |
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2015-12-03 | — | — | US | disclosed |
| EP-2945927-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD AND ITS SALTS | Shilpa Medicare Limited (IN) | 2015-11-25 | — | — | EP | disclosed |
| WO-2014111836-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2014-07-24 | — | — | WO | disclosed |
| EP-1319651-A2 | 2-Aminopropane-1,3-diol compound, pharmaceutical use thereof and synthetic intermediates therefor | Mitsubishi Pharma Corporation (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6214873-B1 | PREVENTION OR SUPPRESION OF REJECTION OF ORGANS OR BONE MARROW TRANSPLANTATION; TREATMENT OF AUTOIMMUNE DISEASES OR ALLERGIC DISEASES; DECREASE IN TOXICITY AND HIGHER SAFETY | WELFIDE CORPORATION (JP) | 2001-04-10 | — | — | US | disclosed |
| CN-1259117-A | 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-07-05 | — | — | CN | disclosed |
| EP-1002792-A1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153684-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD HYDROCHLORIDE | S1PR2, S1PR4, S1PR5 | ALDH1A1 1249/4885RECQL 4797/4885THRB 2451/4885 |
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | S1PR4, S1PR1, S1PR5 | ALDH1A1 2418/4885RECQL 4330/4885THRB 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.