SCHEMBL50365

SCHEMBL50365

O=C(O)C(=O)COP(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TPI1 P60174 2/20 0.50
PGK1 P00558 1/20 0.43
PGK2 P07205 1/20 0.43
PEPD P12955 1/20 0.42
PGD P52209 2/20 0.40
OR51E2 Q9H255 1/20 0.35
LPAR1 Q92633 2/20 0.33
LPAR3 Q9UBY5 2/20 0.33
LPAR2 Q9HBW0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alpha-Ketoglutaric Acid SCHEMBL2030659 0.87 EGLN1 (0.56) TPI1PGK1PGK2PEPDPGD
Phosphoglycolic Acid SCHEMBL20798069 0.78 TPI1 (0.54) TPI1PGK1PGK2PGDLPAR1
Phosphoglycolic Acid SCHEMBL380471 0.78
Glutamic Acid SCHEMBL345401 0.77 GRM8 (0.56)
SCHEMBL21197357 0.77 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR1
SCHEMBL2030661 0.77 TPI1 (0.36) TPI1PGK1PGK2PEPDPGD
Phosphoglycolic Acid SCHEMBL5586781 0.76 TPI1 (0.52) TPI1PGK1PGK2PGDLPAR1
Phosphoglycolic Acid SCHEMBL29156120 0.76 TPI1 (0.52) TPI1PGK1PGK2PGD
SCHEMBL6150390 0.75 TPI1 (0.46) TPI1PGK1PGK2PEPDPGD
SCHEMBL5485133 0.75 TPI1 (0.56) TPI1PGK1PGK2PGDLPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 801 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605521-A2 GENETICALLY MODIFIED HOST CELLS PRODUCING L-SERINE CysBio ApS (DK) 2025-08-27 EP claimed
US-20250215468-A1 METHOD FOR CONVERTING CARBON SOURCE INTO SERINE NAN YA PLASTICS CORPORATION (TW) 2025-07-03 US claimed
WO-2025104134-A9 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CYSBIO APS (DK) 2025-06-19 WO claimed
WO-2025104134-A2 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CYSBIO APS (DK) 2025-05-22 WO claimed
EP-4556561-A1 EXPRESSION OF BIOMOLECULES WITH IMPROVED PROMOTER AND TIR CysBio ApS (DK) 2025-05-21 EP claimed
CN-120005781-A Expression of biomolecules with improved promoters and TIR 赛斯生物私人有限公司 2025-05-16 CN claimed
US-20240385183-A1 METABOLIC AND MICROBIAL BIOMARKERS FOR DETECTION OF PANCREATICOBILIARY CANCERS NORTHWESTERN UNIVERSITY 2024-11-21 US claimed
EP-4381076-A1 MICROORGANISMS AND METHODS FOR IMPROVED BIOLOGICAL PRODUCTION OF ETHYLENE GLYCOL Lanzatech, Inc. (US) 2024-06-12 EP claimed
WO-2024084049-A2 GENETICALLY MODIFIED HOST CELLS PRODUCING L-SERINE CYSBIO APS (DK) 2024-04-25 WO claimed
US-11952607-B2 Microorganisms and methods for improved biological production of ethylene glycol LANZATECH, INC. (US) 2024-04-09 US claimed
EP-0599819-B1 Use of hydroxycarboxylic acids and derivatives for the preparation of topical dermatologic compositions for the treatment of wrinkles SCOTT EUGENE J VAN (US) 1997-04-02 EP claimed
US-5561158-A Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging TRISTRATA, INCORPORATED 1996-10-01 US claimed
US-5561157-A INCLUDES ORGANIC ALPHA AND BETA HYDROXY OR KETO CARBOXYLIC ACIDS, ESTERS, LACTONES AND/OR SALTS; USED FOR SKIN DISORDERS TRISTRATA INC (US) 1996-10-01 US claimed
US-5554654-A COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND TRISTRATA INC (US) 1996-09-10 US claimed
US-5554597-A Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging TRISTRATA INC (US) 1996-09-10 US claimed
US-5554652-A TOPICALLY APPLYING MIXTURE TO REDUCE OR PREVENT SKIN DISORDERS TRISTRATA INC (US) 1996-09-10 US claimed
EP-0273202-B1 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. SCOTT EUGENE J VAN (US) 1995-06-21 EP claimed
EP-0599819-A2 Additives enhancing topical actions of therapeutic agents Van Scott, Eugene J., Dr. (US) 1994-06-01 EP claimed
EP-0273202-A2 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. Van Scott, Eugene J., Dr. (US) 1988-07-06 EP claimed
US-4380549-A ONE OR MORE HYDROXYCARBOXYLIC ACIDS SCOTT EUGENE J VAN 1983-04-19 US claimed