Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14109406 | 0.85 | MAPT (0.57) | SMN1; SMN2KDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL14109982 | 0.82 | HTT (0.46) | SMN1; SMN2RAB9AALDH1A1GAACOPS5 | |
| SCHEMBL4285011 | 0.81 | RAB9A (0.71) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL3413746 | 0.80 | KDM4E (0.65) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL5557330 | 0.80 | COPS5 (0.44) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL13494041 | 0.79 | COPS5 (0.45) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL14108950 | 0.79 | GPR52 (0.57) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL14108836 | 0.77 | KDM4E (0.54) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL5216624 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL3436648 | 0.74 | KDM4E (0.65) | SMN1; SMN2KDM4ERAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2530078-A1 | THIAZOLE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2012-12-05 | — | — | EP | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20050014833-A1 | Cyclic compound and ppar agonist | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1452521-A1 | CYCLIC COMPOUND AND PPAR AGONIST | Eisai Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014833-A1 | Cyclic compound and ppar agonist | PPARA, PPARG, PPARD | SMN1; SMN2 4707/4885KDM4E 2818/4885RAB9A 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.