Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.39 |
| ▸ | MGLL | Q99685 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45163 | 1.00 | FAAH (0.39) | FAAHMGLLALDH1A1NPSR1HSP90AA1 | |
| SCHEMBL5805436 | 0.88 | ALDH1A1 (0.34) | FAAHALDH1A1NPSR1HSP90AA1HPGD | |
| SCHEMBL24393467 | 0.85 | FAAH (0.31) | FAAHMGLL | |
| SCHEMBL27634428 | 0.85 | FAAH (0.32) | FAAHMGLL | |
| SCHEMBL18353699 | 0.85 | NAAA (0.38) | FAAHMGLLTDP1SMN1; SMN2 | |
| SCHEMBL10032833 | 0.84 | FAAH (0.44) | FAAHMGLLALDH1A1NPSR1HSP90AA1 | |
| SCHEMBL15080490 | 0.82 | FAAH (0.40) | FAAHMGLLALDH1A1NPSR1HSP90AA1 | |
| SCHEMBL157132 | 0.82 | MGLL (0.37) | FAAHMGLL | |
| SCHEMBL9055859 | 0.82 | MGLL (0.37) | FAAHMGLL | |
| SCHEMBL43979 | 0.80 | MGLL (0.48) | FAAHMGLLALDH1A1NPSR1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986609-A2 | RNA SILENCING AGENTS FOR USE IN THERAPY AND NANOTRANSPORTERS FOR EFFICIENT DELIVERY OF SAME | University of Massachusetts (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007089607-A2 | RNA SILENCING AGENTS FOR USE IN THERAPY AND NANOTRANSPORTERS FOR EFFICIENT DELIVERY OF SAME | UNIVERSITY OF MASSACHUSETTS (US) | 2007-08-09 | — | — | WO | disclosed |