Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227716 | 0.85 | VCAM1 (0.43) | ALDH1A1KDM4ETSHRLMNAMAPT | |
| SCHEMBL2191814 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRLMNAMAPT | |
| SCHEMBL22095405 | 0.82 | MAPT (0.44) | ALDH1A1KDM4ETSHRMAPTACHE | |
| SCHEMBL3845818 | 0.76 | KMT2A (0.54) | ALDH1A1KDM4ETSHRLMNAMAPT | |
| SCHEMBL8870718 | 0.76 | KMT2A (0.54) | ALDH1A1KDM4ETSHRLMNAMAPT | |
| SCHEMBL7088040 | 0.76 | GAA (0.44) | ALDH1A1TSHRMAPTSMN1; SMN2ACP3 | |
| SCHEMBL3830094 | 0.75 | GAA (0.39) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL11038956 | 0.75 | IDO1 (0.38) | ACHE | |
| SCHEMBL11041179 | 0.75 | TDP1 (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL2610137 | 0.74 | L3MBTL1 (0.42) | ALDH1A1KDM4EHTTACHEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873262-A | Heterogeneous catalyst polycarboxy zinc polymer and application thereof in catalyzing silicon cyanation reaction of benzaldehyde derivative | 广东轻工职业技术学院 | 2023-03-31 | — | — | CN | disclosed |
| CN-115746327-A | Manganese (II) metal catalyst for silicon cyanation reaction of benzaldehyde derivative, and preparation method and application thereof | 广东轻工职业技术学院 | 2023-03-07 | — | — | CN | disclosed |
| CN-112920223-B | Catalyst for silicon cyanation reaction of aldehyde and trimethylsilyl cyanide and preparation method thereof | 兰州大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-112920223-A | Catalyst for silicon cyanation reaction of aldehyde and trimethylsilyl cyanide and preparation method thereof | 兰州大学 | 2021-06-08 | — | — | CN | disclosed |
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |
| US-7129238-B2 | Mandelic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-10-31 | — | — | US | disclosed |
| CN-1714079-A | Mandelic acid derivatives | HOFFMANN LA ROCHE (CH) | 2005-12-28 | — | — | CN | disclosed |
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| US-20040122057-A1 | Novel mandelic acid derivatives | HOFFMANN-LA ROCHE INC. | 2004-06-24 | — | — | US | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122057-A1 | Novel mandelic acid derivatives | F7, F11, F9 | ALDH1A1 519/4885KDM4E 2563/4885TSHR 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.