Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14186683 | 1.00 | NOD1 (0.47) | NOD1CASP2FAAHCNR1NAAA | |
| SCHEMBL5034461 | 0.87 | FAAH (0.46) | NOD1CASP2FAAHDNM1EPHX2 | |
| SCHEMBL6018656 | 0.84 | CYP3A4 (0.51) | MAPTKMT2A | |
| SCHEMBL7342396 | 0.81 | CA1 (0.44) | NOD1CASP2 | |
| SCHEMBL5038748 | 0.81 | CA1 (0.35) | NOD1FAAHCNR1MEN1KMT2A | |
| SCHEMBL14367745 | 0.81 | CA1 (0.44) | NOD1CASP2 | |
| SCHEMBL14367747 | 0.78 | PAOX (0.38) | NOD1 | |
| SCHEMBL10521386 | 0.78 | AKR1B1 (0.39) | MEN1KMT2A | |
| SCHEMBL2704033 | 0.78 | AKR1B1 (0.39) | MEN1KMT2A | |
| SCHEMBL2704035 | 0.78 | AKR1B1 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | disclosed |
| US-7112612-B2 | N-alkylated GABA compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2006-09-26 | — | — | US | disclosed |