Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041727 | 0.90 | MAPK1 (0.48) | MAPK1KMT2APDE4DPDE4APDE4B | |
| SCHEMBL5041669 | 0.87 | KAT2B (0.52) | KAT2BBAZ2BMAPK1IDH2PDE4D | |
| SCHEMBL4424161 | 0.83 | SLC6A9 (0.53) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL5043148 | 0.78 | MAPK1 (0.49) | MAPK1IDH2SYKALDH1A1L3MBTL1 | |
| SCHEMBL11460936 | 0.78 | MAPK1 (0.69) | MAPK1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL15144072 | 0.77 | BRD4 (0.49) | KAT2BBAZ2BPDE4DPDE4APDE4B | |
| SCHEMBL5045483 | 0.76 | FABP4 (0.43) | MAPK1KMT2APDE4DPDE4APDE4B | |
| SCHEMBL2825503 | 0.76 | FABP4 (0.45) | MAPK1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3931172 | 0.74 | SMN1; SMN2 (0.65) | KMT2AALDH1A1SLC6A9 | |
| SCHEMBL25314851 | 0.73 | KAT2B (0.50) | KAT2BBAZ2BKMT2APDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656361-B1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |