Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 4/20 | 0.44 |
| ▸ | GABRD | O14764 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.44 |
| ▸ | GABRE | P78334 | 4/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL1810585 | 0.87 | ALDH1A1 (0.61) | PARP1ALDH1A1GPR3HSD17B10GABRP | |
| SCHEMBL5933739 | 0.87 | IMPDH2 (0.63) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 | |
| SCHEMBL5040493 | 0.85 | GABRP (0.42) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 | |
| SCHEMBL22141444 | 0.85 | PARP1 (0.49) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 | |
| SCHEMBL866840 | 0.85 | IMPDH2 (0.61) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 | |
| SCHEMBL1326375 | 0.85 | IMPDH2 (0.61) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 | |
| SCHEMBL17807934 | 0.83 | PARP1 (0.51) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 | |
| SCHEMBL29819506 | 0.83 | PARP1 (0.51) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 | |
| SCHEMBL20199521 | 0.82 | PARP1 (0.50) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 | |
| SCHEMBL19980374 | 0.82 | KDM4E (0.41) | IMPDH2IMPDH1PARP1ALDH1A1GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080036365-A1 | Carbazole Derivative Containing Fluorene Group and Organic Electroluminescent Element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2008-02-14 | — | — | US | disclosed |