SCHEMBL503852

SCHEMBL503852

C=CC(=O)Nc1cc(NC(=O)C=C)cc(C(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 10/20 0.57
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
F13A1 P00488 1/20 0.48
LMNA P02545 1/20 0.48
TGM1 P22735 1/20 0.48
TGM3 Q08188 1/20 0.48
POLB P06746 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776267 0.96 TGM2 (0.57) TGM2MEN1KMT2AF13A1LMNA
SCHEMBL19911213 0.90 LPAR2 (0.56) TGM2MEN1KMT2ALMNAPOLB
SCHEMBL16053417 0.87 TGM2 (0.64) TGM2F13A1LMNATGM1TGM3
SCHEMBL1668968 0.82 TGM2 (0.65) TGM2MEN1KMT2ALMNA
SCHEMBL20839770 0.80 KDM4E (0.57) TGM2MEN1KMT2AF13A1LMNA
SCHEMBL890715 0.80 TGM2 (0.68) TGM2MEN1KMT2AF13A1LMNA
SCHEMBL19911212 0.80 NSD2 (0.59) TGM2MEN1KMT2AF13A1LMNA
SCHEMBL20278504 0.79 CA1 (0.45) TGM2MEN1KMT2AF13A1LMNA
Hydroxyl Radical SCHEMBL28150321 0.78 TGM2 (0.66) TGM2MEN1KMT2AF13A1LMNA
SCHEMBL16269020 0.78 LPAR2 (0.65) MEN1KMT2ALMNAPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048382-A1 HYPER-CROSS-LINKED POLYAMIDE/POLYAMINE 3D-NETWORK FOR WATER TREATMENT KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-02-19 US claimed
CN-116178608-B Method for preparing two-dimensional copolymer by utilizing hydrogen bond induction assembly 安徽大学 2025-03-25 CN claimed
CN-118829398-A System and method for a personal wearable electronic device 麻省理工学院 2024-10-22 CN claimed
US-20240181430-A1 POROUS SORPTIVE SOLID PHASE MICROEXTRACTION DEVICES AND PREPARATION THEREOF MEMORIAL UNIVERSITY OF NEWFOUNDLAND (CA) 2024-06-06 US claimed
EP-4306556-A1 PROTIC IONIC LIQUID BASED ON DIALLYL AMMONIUM CATION AND RELATED MEMBRANE Toyota Jidosha Kabushiki Kaisha (JP) 2024-01-17 EP claimed
EP-4294559-A1 POROUS SORPTIVE SOLID PHASE MICROEXTRACTION DEVICES AND PREPARATION THEREOF Memorial University of Newfoundland (CA) 2023-12-27 EP claimed
US-20230277159-A1 SYSTEMS AND METHODS FOR ON-PERSON WEARABLE ELECTRONIC DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2023-09-07 US claimed
CN-114835853-A Method for circularly preparing and purifying D-tagatose by using phenylboronic acid-based carrier column 江南大学 2022-08-02 CN claimed
WO-2016189141-A1 METHOD FOR THE DETERMINATION OF TARGETS OF BIOTINYLATED MOLECULES UNIVERSITAT AUTONOMA DE BARCELONA (ES) 2016-12-01 WO claimed
EP-2368897-B1 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays CORNELL RES FOUNDATION INC (US) 2016-10-19 EP claimed
EP-1618382-A1 IMPROVED COMPOSITE MICROARRY SLIDES Cuno, Inc. (US) 2006-01-25 EP claimed
US-20050233320-A1 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RESEARCH FOUNDATION, INC. 2005-10-20 US claimed
WO-2004095025-A1 IMPROVED COMPOSITE MICROARRY SLIDES CUNO, INC. (US) 2004-11-04 WO claimed
EP-0920440-A4 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RES FOUNDATION INC (US) 2004-08-25 EP claimed
US-20030219816-A1 Composite microarray slides 3M INNOVATIVE PROPERTIES COMPANY 2003-11-27 US claimed
US-20030148284-A1 Solid phase detection of nucleic acid molecules CORNING INCORPORATED 2003-08-07 US claimed
US-20030022182-A1 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays CORNELL RESEARCH FOUNDATION, INC. 2003-01-30 US claimed
JP-2001519648-A 2001-10-23 JP claimed
EP-0920440-A2 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RESEARCH FOUNDATION, INC. (US) 1999-06-09 EP claimed
WO-1997031256-A2 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RESEARCH FOUNDATION, INC. (US) 1997-08-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048382-A1 HYPER-CROSS-LINKED POLYAMIDE/POLYAMINE 3D-NETWORK FOR WATER TREATMENT H1-3, TET3, PAM TGM2 615/4885MEN1 1594/4885KMT2A 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.