Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562999 | 0.85 | TSHR (0.47) | EPHX2CA2CA7TSHR | |
| SCHEMBL4941280 | 0.85 | TSHR (0.47) | EPHX2CA2CA7TSHR | |
| SCHEMBL563000 | 0.85 | TSHR (0.47) | EPHX2CA2CA7TSHR | |
| SCHEMBL5037810 | 0.83 | CYP1A2 (0.49) | GAAKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL4940078 | 0.83 | CYP1A2 (0.49) | GAAKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL4944206 | 0.83 | CYP1A2 (0.49) | GAAKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL27777706 | 0.82 | EPHX2 (0.39) | EPHX2CTSKCTSSCAPN1MEN1 | |
| SCHEMBL5038748 | 0.81 | CA1 (0.35) | MEN1KMT2ACA1CA2CYP1A2 | |
| SCHEMBL5037132 | 0.81 | LMNA (0.49) | EPHX2GAAHTT | |
| SCHEMBL27756899 | 0.81 | KDM4E (0.40) | EPHX2CTSKCAPN1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | claimed |
| US-7112612-B2 | N-alkylated GABA compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2006-09-26 | — | — | US | claimed |
| US-20040058991-A1 | N-alkylated gaba compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2004-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058991-A1 | N-alkylated gaba compounds, processes for their preparation and their use as medicaments | GABBR1, GABRB1, GABRB2 | EPHX2 2178/4885CTSK 3576/4885CTSS 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.