SCHEMBL503962

SCHEMBL503962

CCOc1ccc2ccccc2c1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
HSD17B10 Q99714 2/20 0.61
LMNA P02545 1/20 0.61
TSHR P16473 1/20 0.61
RAB9A P51151 1/20 0.61
CXCR5 P32302 1/20 0.58
AVPR1A P37288 2/20 0.55
AVPR1B P47901 1/20 0.55
TP53 P04637 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 2/20 0.50
HCRTR1 O43613 3/20 0.49
HCRTR2 O43614 3/20 0.49
CTSD P07339 1/20 0.49
ALOX5 P09917 1/20 0.49
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
GLA P06280 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30393029 1.00 ALDH1A1 (0.61) ALDH1A1HSD17B10LMNATSHRRAB9A
Hydrochloric Acid SCHEMBL1037379 0.98 ALDH1A1 (0.60) ALDH1A1HSD17B10LMNATSHRRAB9A
SCHEMBL4340803 0.88 CNR1 (0.57) ALDH1A1HSD17B10LMNATSHRRAB9A
SCHEMBL18288073 0.88 ALDH1A1 (0.58) ALDH1A1HSD17B10LMNATSHRRAB9A
SCHEMBL4539589 0.87 ALDH1A1 (0.60) ALDH1A1HSD17B10LMNATSHRRAB9A
SCHEMBL5404802 0.87 ALDH1A1 (0.52) ALDH1A1HSD17B10LMNATSHRRAB9A
SCHEMBL10935027 0.87 ALDH1A1 (0.52) ALDH1A1HSD17B10LMNATSHRRAB9A
SCHEMBL17509546 0.86 GAA (0.59) ALDH1A1HSD17B10LMNATSHRRAB9A
SCHEMBL6460843 0.86 ALDH1A1 (0.59) ALDH1A1HSD17B10LMNATSHRRAB9A
SCHEMBL627877 0.86 ALDH1A1 (0.59) ALDH1A1HSD17B10LMNATSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117416983-A Naphthoxyhc acid and/or its derivative acid radical intercalation hydrotalcite-like compound and its preparation method 中国科学院青海盐湖研究所 2024-01-19 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-106748604-B Method for synthesizing mono-iodo aromatic hydrocarbon or di-iodo aromatic hydrocarbon based on decarboxylation of aromatic carboxylic acid 湘潭大学 2020-06-05 CN claimed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
CN-108238894-A The synthetic method of sodium ethoxynaphthamidopenicillanate pharmaceutical intermediate 2- ethoxy naphthoic acids 成都切斯特科技有限公司 2018-07-03 CN claimed
CN-104356143-B A kind of preparation method of naphthlazole acid 桂林南药股份有限公司 2017-08-29 CN claimed
CN-106748604-A A kind of method for synthesizing single iodo aromatic hydrocarbon or two iodo aromatic hydrocarbons based on aromatic carboxylic acid's decarboxylic reaction 湘潭大学 2017-05-31 CN claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060040923-A1 Benzodiazepine derivatives and pharmaceutical compositions containing them ARROW THERAPEUTICS LIMITED (GB) 2006-02-23 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
WO-2005090319-A1 PROCESS FOR PREPARING BENZODIAZEPINES ARROW THERAPEUTICS LIMITED (GB) 2005-09-29 WO claimed
WO-2005089769-A1 PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBIT OR OF THE RSV FUSION PROTEIN ARROW THERAPEUTICS LIMITED (GB) 2005-09-29 WO claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS ALDH1A1 3087/4885HSD17B10 2420/4885LMNA 4734/4885
US-20060040923-A1 Benzodiazepine derivatives and pharmaceutical compositions containing them GABRA6, CNR1, SIGMAR1 ALDH1A1 2127/4885HSD17B10 1433/4885LMNA 1425/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS ALDH1A1 3087/4885HSD17B10 2420/4885LMNA 4734/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 ALDH1A1 1569/4885HSD17B10 2219/4885LMNA 1769/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 ALDH1A1 1723/4885HSD17B10 2365/4885LMNA 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.