SCHEMBL504038

SCHEMBL504038

C=CCC(N)(CC=C)C(=C)C(=C)C(N)(CC=C)CC=C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13727785 0.83 HTT (0.36) ALDH1A1TSHR
SCHEMBL2050206 0.76
SCHEMBL9249182 0.74 HTT (0.36) ALDH1A1TSHR
SCHEMBL30651 0.72 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL10644907 0.72 HTT (0.44) ALDH1A1TSHR
SCHEMBL7038085 0.71
SCHEMBL11237698 0.69
SCHEMBL6280867 0.69
Hydrochloric Acid SCHEMBL10425340 0.69
SCHEMBL127487 0.67 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US claimed
US-11912798-B2 Rubber with backbone and end-group functionalization THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-02-27 US disclosed
US-20220177610-A1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2022-06-09 US disclosed
US-20220169752-A1 METHOD OF MAKING A SILICA/CELLULOSE HYBRID THE GOODYEAR TIRE & RUBBER COMPANY 2022-06-02 US disclosed
US-9587060-B2 Functionalized rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-03-07 US disclosed
US-9550839-B2 Copolymers of conjugated triene monomers for improved filler interaction THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-01-24 US disclosed
US-20150376343-A1 COPOLYMERS OF CONJUGATED TRIENE MONOMERS FOR IMPROVED FILLER INTERACTION THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-12-31 US disclosed
US-9079980-B2 Copolymers of conjugated triene monomers for improved filler interaction THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-07-14 US disclosed
US-8299290-B2 Boron containing functionalizing agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-10-30 US disclosed
US-20120048446-A1 COPOLYMERS OF CONJUGATED TRIENE MONOMERS FOR IMPROVED FILLER INTERACTION THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-03-01 US disclosed
US-6630552-B1 Butadiene-styrene copolymers with heterocyclic amine compounds THE GOODYEAR TIRE & RUBBER COMPANY 2003-10-07 US disclosed
US-6627722-B2 Rubber comprising comonomers of conjugated diolefin and vinyllaromatic compound substituted with N-heterocycle; tire treads GOODYEAR TIRE & RUBBER COMPANY, THE 2003-09-30 US disclosed
US-6627721-B1 Rubbery polymer comprised of comonomers of conjugated diene and styrene substited with N-heterocycle or sulfide; hoses, power transmission belts THE GOODYEAR TIRE & RUBBER COMPANY 2003-09-30 US disclosed
US-20030134997-A1 Functionalized elastomers THE GOODYEAR TIRE & RUBBER COMPANY 2003-07-17 US disclosed
US-6583260-B2 Such as 2-(N,N-dimethylaminomethyl)-1,3- butadiene); for use in adhesives, sealants, surfactants, elastomers, ionomers, coatings and membranes IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2003-06-24 US disclosed
US-6583260-B2 Such as 2-(N,N-dimethylaminomethyl)-1,3- butadiene); for use in adhesives, sealants, surfactants, elastomers, ionomers, coatings and membranes IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2003-06-24 US disclosed
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US disclosed
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US disclosed
US-6344538-B1 REACTION OF 3-BROMOMETHYL-2,5-HYDROTHIOPHENE-1,1-DIOXIDE WITH NUCLEOPHILE WITH AMINE, HYDROXY, CARBOXY ACID, ESTER OR NITRILE IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2002-02-05 US disclosed
US-6344538-B1 REACTION OF 3-BROMOMETHYL-2,5-HYDROTHIOPHENE-1,1-DIOXIDE WITH NUCLEOPHILE WITH AMINE, HYDROXY, CARBOXY ACID, ESTER OR NITRILE IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2002-02-05 US disclosed