Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644907 | 0.81 | HTT (0.44) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL30651 | 0.81 | ALDH1A1 (0.42) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL30787966 | 0.75 | ARG2 (0.41) | HTTALDH1A1TSHR | |
| SCHEMBL13727785 | 0.75 | HTT (0.36) | HTTALDH1A1TSHR | |
| SCHEMBL504038 | 0.74 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL22712806 | 0.74 | — | — | |
| SCHEMBL5904292 | 0.74 | ALDH1A1 (0.50) | HTTALDH1A1TSHR | |
| SCHEMBL8586862 | 0.74 | CYP2C19 (0.37) | HTTALDH1A1 | |
| SCHEMBL11087825 | 0.74 | ODC1 (0.48) | HTTALDH1A1TSHR | |
| SCHEMBL3852641 | 0.74 | HTT (0.39) | HTTALDH1A1TSHRFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410066-A | Process for the preparation of substituted pyrazolines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | claimed |
| US-5380868-A | Process for the preparation of substituted pyrazolines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | claimed |