Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | ODC1 | P11926 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 5/20 | 0.32 |
| ▸ | ARG1 | P05089 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30787966 | 0.88 | ARG2 (0.41) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| SCHEMBL1416684 | 0.86 | ALDH1A1 (0.37) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| SCHEMBL1416683 | 0.86 | ALDH1A1 (0.37) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| SCHEMBL5904292 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| SCHEMBL3854199 | 0.86 | ALDH1A1 (0.37) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| SCHEMBL11087825 | 0.86 | ODC1 (0.48) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL2302947 | 0.86 | ARG2 (0.40) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| SCHEMBL3852730 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| SCHEMBL29962101 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TSHRHTTMEN1CYP1A2 | |
| SCHEMBL3852726 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TSHRHTTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12023389-B2 | Compositions that target tumor-associated macrophages and methods of use therefor | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240150397-A1 | TARGETED DELIVERY SYSTEM AND METHODS OF USE THEREFOR | Sanford Burnham Prebys Medical Discovery Institute | 2024-05-09 | — | — | US | disclosed |
| US-20240131201-A1 | COMPOSITIONS THAT TARGET TUMOR-ASSOCIATED MACROPHAGES AND METHODS OF USE THEREFOR | Sanford Burnham Prebys Medical Discovery Institute | 2024-04-25 | — | — | US | disclosed |
| US-20240117006-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2024-04-11 | — | — | US | disclosed |
| US-20230414704-A1 | Compositions Containing a Pharmacophore with Selectivity to Diseased Tissue and Methods of Making Same | SANFORD-BURNHAM MEDICAL DISCOVERY INSTITUTE | 2023-12-28 | — | — | US | disclosed |
| EP-3912986-B1 | CRP CAPTURE/DETECTION OF BACTERIA | HARVARD COLLEGE (US) | 2023-12-13 | — | — | EP | disclosed |
| US-11807677-B2 | Microbe-binding molecules and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-11-07 | — | — | US | disclosed |
| US-11795212-B2 | Engineered microbe-targeting molecules and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-24 | — | — | US | disclosed |
| US-11718651-B2 | CRP capture/detection of gram positive bacteria | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-08 | — | — | US | disclosed |
| US-11642391-B2 | Compositions containing a pharmacophore with selectivity to diseased tissue and methods of making same | VASCULAR BIOSCIENCES (US) | 2023-05-09 | — | — | US | disclosed |
| US-20030232762-A1 | Breast homing peptides and methods of identifying same using aminopeptidase P | BURNHAM INSTITUTE FOR MEDICAL RESEARCH | 2003-12-18 | — | — | US | disclosed |
| US-20030143651-A1 | Fret protease assays for clostridial toxins | ALLERGAN, INC. | 2003-07-31 | — | — | US | disclosed |
| US-20030143650-A1 | Fret protease assays for botulinum serotype A/E toxins | ALLERGAN, INC. | 2003-07-31 | — | — | US | disclosed |
| US-20030077664-A1 | Methods of screening for compounds that modulate hormone receptor activity | ADVANCED MEDICAL OPTICS, INC. | 2003-04-24 | — | — | US | disclosed |
| WO-2003020948-A2 | FRET PROTEASE ASSAYS FOR BOTULINUM SEROTYPE A/E TOXINS | ALLERGAN, INC. (US) | 2003-03-13 | — | — | WO | disclosed |
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240117006-A1 | MODIFIED INTEGRIN POLYPEPTIDES, MODIFIED INTEGRIN POLYPEPTIDE DIMERS, AND USES THEREOF | ITGA2B, ITGB1, ITGA1 | ALDH1A1 2700/4885TSHR 583/4885HTT 3937/4885 |
| US-20030232762-A1 | Breast homing peptides and methods of identifying same using aminopeptidase P | DNPEP, ANPEP, DPEP1 | ALDH1A1 1359/4885TSHR 3484/4885HTT 4469/4885 |
| US-20030143650-A1 | Fret protease assays for botulinum serotype A/E toxins | BTD, ADAM33, ADAM17 | ALDH1A1 3750/4885TSHR 1765/4885HTT 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.