Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163395 | 0.84 | KMT2A (0.53) | FABP4FABP5POLBHTTNPSR1 | |
| SCHEMBL9445850 | 0.84 | KMT2A (0.53) | FABP4FABP5POLBHTTNPSR1 | |
| SCHEMBL9445847 | 0.84 | KMT2A (0.53) | FABP4FABP5POLBHTTNPSR1 | |
| SCHEMBL2349656 | 0.83 | CES2 (0.46) | FABP4FABP5POLBL3MBTL1KMT2A | |
| SCHEMBL8523806 | 0.78 | POLB (0.43) | POLBHTTNPSR1L3MBTL1CA12 | |
| SCHEMBL5040787 | 0.77 | CA12 (0.44) | FABP4FABP5HTTNPSR1CA12 | |
| SCHEMBL11556826 | 0.77 | FABP4 (0.49) | FABP4FABP5POLBHTTNPSR1 | |
| SCHEMBL17724548 | 0.76 | ALDH1A1 (0.51) | FABP4FABP5L3MBTL1KMT2AKDM4E | |
| SCHEMBL5037418 | 0.76 | ALDH1A1 (0.51) | FABP4FABP5L3MBTL1KMT2AKDM4E | |
| SCHEMBL31114370 | 0.76 | POLB (0.44) | POLBHTTNPSR1L3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |