Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445847 | 1.00 | KMT2A (0.53) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL9445850 | 1.00 | KMT2A (0.53) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL11556826 | 0.88 | FABP4 (0.49) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL5041723 | 0.84 | FABP4 (0.46) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL1631629 | 0.84 | POLB (0.55) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL29430260 | 0.84 | POLB (0.55) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL10369275 | 0.84 | KMT2A (0.49) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL9445845 | 0.81 | LMNA (0.45) | L3MBTL1FABP4FABP5LMNAALDH1A1 | |
| SCHEMBL9445842 | 0.81 | LMNA (0.45) | L3MBTL1FABP4FABP5LMNAALDH1A1 | |
| SCHEMBL9445841 | 0.81 | LMNA (0.45) | L3MBTL1FABP4FABP5LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116338-A | Synthesis method of 1- (4-hydroxy-3, 5-dimethoxyphenyl) ethane-1-ketone | 苏州汉德创宏生化科技有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-111116338-A | Synthesis method of 1- (4-hydroxy-3, 5-dimethoxyphenyl) ethane-1-ketone | 苏州汉德创宏生化科技有限公司 | 2020-05-08 | — | — | CN | disclosed |
| US-5430060-A | Aldose reductase inhibitor | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| EP-0469887-A1 | Acetamide derivatives | ZENECA LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |