Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
| ▸ | CBFB | Q13951 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 6/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503528 | 0.81 | CCR1 (0.47) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL14460983 | 0.79 | METAP2 (0.36) | CBFBNOS3NOS2NPC1RAB9A | |
| SCHEMBL12750071 | 0.78 | NPC1 (0.32) | NPC1RAB9ANR1H2NR1H3PIM1 | |
| SCHEMBL29756493 | 0.78 | METAP2 (0.36) | CBFBNOS3NOS2NPC1RAB9A | |
| SCHEMBL31406166 | 0.75 | KDM4E (0.59) | DYRK1ANPC1RAB9ANR1H2NR1H3 | |
| SCHEMBL18678742 | 0.73 | CCR1 (0.53) | CCR1CCR5CCR8CBFBNOS3 | |
| SCHEMBL503439 | 0.73 | L3MBTL1 (0.60) | CCR1CCR5CCR8CBFBPLAU | |
| SCHEMBL12750083 | 0.73 | NPC1 (0.37) | CBFBPLAUNPC1RAB9A | |
| SCHEMBL18678649 | 0.73 | KDM5B (0.31) | — | |
| SCHEMBL29635188 | 0.72 | L3MBTL1 (0.58) | CCR1CCR5CCR8CBFBPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | SOLVAY SA (BE) | 2012-02-02 | — | — | US | disclosed |
| EP-2393820-A1 | PHOSPHORESCENT LIGHT-EMITTING IRIDIUM COMPLEX CONTAINING PYRIDYLTRIAZOLE LIGAND | Solvay SA (BE) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010090362-A1 | PHOSPHORESCENT LIGHT-EMITTING IRIDIUM COMPLEX CONTAINING PYRIDYLTRIAZOLE LIGAND | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | PPIP5K2, HPRT1, PHPT1 | CCR1 3890/4885CCR5 3260/4885CCR8 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.