Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28440735 | 0.88 | CCR1 (0.44) | CCR1CCR5CCR8METAP2PTGS2 | |
| SCHEMBL14460983 | 0.82 | METAP2 (0.36) | METAP2NPC1ALPLPKMALOX15 | |
| SCHEMBL18678649 | 0.82 | KDM5B (0.31) | METAP2KDM5B | |
| SCHEMBL29756493 | 0.81 | METAP2 (0.36) | METAP2NPC1ALPLPKMALOX15 | |
| SCHEMBL12750071 | 0.81 | NPC1 (0.32) | NPC1ALPLPKMALOX15RAB9A | |
| SCHEMBL504223 | 0.81 | CCR1 (0.51) | CCR1CCR5CCR8CYP2A6NPC1 | |
| SCHEMBL15907865 | 0.79 | CCR1 (0.55) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL503439 | 0.76 | L3MBTL1 (0.60) | CCR1CCR5CCR8METAP2HPGD | |
| SCHEMBL12750083 | 0.76 | NPC1 (0.37) | NPC1ALPLPKMALOX15RAB9A | |
| SCHEMBL29635188 | 0.75 | L3MBTL1 (0.58) | CCR1CCR5CCR8METAP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10862049-B2 | Composition, organic-electroluminescence-device material, composition film, organic electroluminescence device, and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2020-12-08 | — | — | US | disclosed |
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | SOLVAY SA (BE) | 2012-02-02 | — | — | US | disclosed |
| EP-2393820-A1 | PHOSPHORESCENT LIGHT-EMITTING IRIDIUM COMPLEX CONTAINING PYRIDYLTRIAZOLE LIGAND | Solvay SA (BE) | 2011-12-14 | — | — | EP | disclosed |
| US-7915414-B2 | Blue-emitting organometallic complexes and their application | Chi, Yun (TW) | 2011-03-29 | — | — | US | disclosed |
| WO-2010090362-A1 | PHOSPHORESCENT LIGHT-EMITTING IRIDIUM COMPLEX CONTAINING PYRIDYLTRIAZOLE LIGAND | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2010-08-12 | — | — | WO | disclosed |
| US-20080125591-A1 | Blue-Emitting Organometallic Complexes And Their Application | Chi, Yun (TW) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10862049-B2 | Composition, organic-electroluminescence-device material, composition film, organic electroluminescence device, and electronic device | PIEZO1, C1S, C5 | CCR1 1971/4885CCR5 3365/4885CCR8 3700/4885 |
| US-20080125591-A1 | Blue-Emitting Organometallic Complexes And Their Application | CYBA, IK, CRY1 | CCR1 4516/4885CCR5 3708/4885CCR8 4712/4885 |
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | PPIP5K2, HPRT1, PHPT1 | CCR1 3890/4885CCR5 3260/4885CCR8 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.