Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 2/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160309 | 0.86 | HNF4A (0.59) | HNF4AAKR1C2AKR1C1BRS3LTB4R2 | |
| SCHEMBL543491 | 0.81 | RARB (0.57) | HNF4AKAT8PPARA | |
| SCHEMBL31220658 | 0.81 | RARB (0.53) | KAT8PPARAPTPN11 | |
| SCHEMBL11682848 | 0.80 | PPARA (0.63) | HNF4AAKR1C2AKR1C1KAT8PPARA | |
| Ammonia Solution, Strong SCHEMBL29170964 | 0.79 | PTPN11 (0.45) | AKR1C2AKR1C1KAT8PPARAPTPN11 | |
| Phthalic Acid SCHEMBL27978921 | 0.79 | PPARA (0.58) | KAT8PPARAPTPN11 | |
| SCHEMBL27892535 | 0.78 | MAPK8 (0.47) | AKR1C2AKR1C1KAT8PPARAPTPN11 | |
| SCHEMBL28400225 | 0.77 | HTR7 (0.53) | — | |
| SCHEMBL14324808 | 0.77 | LPL (0.49) | KAT8PPARA | |
| SCHEMBL10598324 | 0.77 | PTPN11 (0.52) | HNF4APTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601652-B1 | PYRIDINIUM SALTS, COMPOUNDS AND METHODS OF USE | MYCOSOL INC (US) | 2008-07-30 | — | — | EP | claimed |