Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179526 | 0.89 | TP53 (0.42) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7180822 | 0.86 | ATM (0.39) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7175430 | 0.84 | LMNA (0.41) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7182193 | 0.82 | HPGD (0.37) | MAPTKDM4EHSD17B10MAPK1LMNA | |
| SCHEMBL7175680 | 0.82 | HPGD (0.40) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7188320 | 0.81 | MAPT (0.42) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7189208 | 0.81 | TAS1R3 (0.35) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7189545 | 0.81 | KMT2A (0.36) | MAPTKDM4EHSD17B10MAPK1LMNA | |
| SCHEMBL7190266 | 0.80 | MAPT (0.39) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7180492 | 0.79 | NPSR1 (0.40) | MAPTKDM4EMAPK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439401-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-20060247436-A1 | Process for preparing acylphosphanes and derivatives thereof | IGM GROUP B.V. (NL) | 2006-11-02 | — | — | US | disclosed |
| EP-1648908-B1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | CIBA SC HOLDING AG (CH) | 2006-10-18 | — | — | EP | disclosed |
| EP-1648908-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | Ciba SC Holding AG (CH) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005014605-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247436-A1 | Process for preparing acylphosphanes and derivatives thereof | PHOSPHO1, PLA2G2C, SGMS2 | MAPT 4646/4885KDM4E 4208/4885HSD17B10 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.