Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67541 | 0.83 | TSHR (0.47) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL1735174 | 0.81 | CFTR (0.48) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL28409674 | 0.81 | TSHR (0.46) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL10060105 | 0.80 | TSHR (0.39) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL5043810 | 0.80 | LMNA (0.41) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL10954100 | 0.77 | TSHR (0.41) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL57751 | 0.76 | POLB (0.43) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL28417022 | 0.76 | ALDH1A1 (0.43) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9484276 | 0.76 | ALDH1A1 (0.45) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9485035 | 0.75 | HDAC3 (0.50) | TSHRALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439401-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439401-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439401-B2 | Process for preparing acylphosphanes and derivatives thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-20060247436-A1 | Process for preparing acylphosphanes and derivatives thereof | IGM GROUP B.V. (NL) | 2006-11-02 | — | — | US | disclosed |
| EP-1648908-B1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | CIBA SC HOLDING AG (CH) | 2006-10-18 | — | — | EP | disclosed |
| EP-1648908-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | Ciba SC Holding AG (CH) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005014605-A1 | PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247436-A1 | Process for preparing acylphosphanes and derivatives thereof | PHOSPHO1, PLA2G2C, SGMS2 | TSHR 3192/4885ALDH1A1 944/4885GAA 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.