Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Protirelin SCHEMBL16091769 | 0.81 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL10087855 | 0.81 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL33419 | 0.81 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL10087946 | 0.81 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL4406163 | 0.80 | TRHR (0.93) | TRHR | |
| SCHEMBL4956855 | 0.80 | TRHR (0.66) | TRHR | |
| SCHEMBL30493140 | 0.80 | TRHR (0.73) | TRHR | |
| SCHEMBL4955742 | 0.79 | TRHR (0.71) | TRHR | |
| SCHEMBL7644944 | 0.79 | TRHR (0.71) | TRHR | |
| Hydrochloric Acid SCHEMBL5735691 | 0.79 | TRHR (0.67) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1901763-A2 | THYROTROPIN-RELEASING HORMONE ANALOGS AND METHOD OF USE | Roger Williams Hospital (US) | 2008-03-26 | — | — | EP | claimed |
| WO-2006096829-A2 | THYROTROPIN-RELEASING HORMONE ANALOGS AND METHOD OF USE | ROGER WILLIAMS HOSPITAL (US) | 2006-09-14 | — | — | WO | claimed |
| EP-1901763-A2 | THYROTROPIN-RELEASING HORMONE ANALOGS AND METHOD OF USE | Roger Williams Hospital (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2006096829-A2 | THYROTROPIN-RELEASING HORMONE ANALOGS AND METHOD OF USE | ROGER WILLIAMS HOSPITAL (US) | 2006-09-14 | — | — | WO | disclosed |