SCHEMBL7644944

SCHEMBL7644944

NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCC(=O)N1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRHR P34981 5/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4955742 1.00 TRHR (0.71) TRHR
SCHEMBL1369526 0.92 TRHR (0.68) TRHR
SCHEMBL7429579 0.87 TRHR (0.58) TRHR
SCHEMBL8260031 0.87 TRHR (0.55) TRHR
SCHEMBL14028677 0.87 TRHR (0.55) TRHR
SCHEMBL14185753 0.84 TRHR (0.68) TRHR
SCHEMBL3132248 0.84 TRHR (0.68) TRHR
SCHEMBL30493140 0.84 TRHR (0.73) TRHR
SCHEMBL1373186 0.83 TRHR (0.65) TRHR
SCHEMBL7273818 0.83 TRHR (0.56) TRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6475989-B1 Use of pyroglutamyl-glutamyl-prolyl amide (EEP) for neurological and neurobehavioral disorders REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2002-11-05 — — US disclosed
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