Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22265515 | 0.87 | L3MBTL1 (0.68) | L3MBTL1MGLLNAAASIGMAR1NAMPT | |
| SCHEMBL28929238 | 0.87 | L3MBTL1 (0.68) | L3MBTL1MGLLNAAASIGMAR1NAMPT | |
| SCHEMBL5048059 | 0.83 | HDAC1 (0.58) | L3MBTL1NAAANAMPTMLYCDCA2 | |
| SCHEMBL6358663 | 0.81 | MGLL (0.62) | L3MBTL1MGLLNAAASIGMAR1NAMPT | |
| SCHEMBL5140092 | 0.81 | L3MBTL1 (0.51) | L3MBTL1NAAAMLYCDCA2HDAC3 | |
| SCHEMBL5132927 | 0.80 | NAAA (0.61) | L3MBTL1NAAANAMPTMLYCDHDAC3 | |
| SCHEMBL5546309 | 0.80 | NAMPT (0.67) | L3MBTL1MGLLSIGMAR1NAMPTEPHX2 | |
| SCHEMBL5515823 | 0.80 | NAMPT (0.67) | L3MBTL1MGLLSIGMAR1NAMPTEPHX2 | |
| SCHEMBL20707157 | 0.80 | NAMPT (0.67) | L3MBTL1MGLLSIGMAR1NAMPTEPHX2 | |
| SCHEMBL5543873 | 0.80 | NAMPT (0.67) | L3MBTL1MGLLSIGMAR1NAMPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |