Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046108 | 0.82 | PPARG (0.48) | MLYCDNAAAEPHX2PPARGL3MBTL1 | |
| SCHEMBL5048860 | 0.79 | MLYCD (0.53) | MLYCDNAAAEPHX2PPARGL3MBTL1 | |
| SCHEMBL5044057 | 0.77 | EPHX2 (0.55) | MLYCDNAAAEPHX2PPARGL3MBTL1 | |
| SCHEMBL5049002 | 0.76 | LTA4H (0.43) | — | |
| SCHEMBL28929298 | 0.74 | MLYCD (0.76) | MLYCDNAAAEPHX2L3MBTL1HDAC3 | |
| SCHEMBL5044168 | 0.74 | ALDH1A1 (0.47) | MLYCDNAAAEPHX2PPARGL3MBTL1 | |
| SCHEMBL5045562 | 0.74 | ALDH1A1 (0.47) | MLYCDNAAAEPHX2PPARGL3MBTL1 | |
| SCHEMBL5044173 | 0.74 | MLYCD (0.54) | MLYCDNAAAEPHX2L3MBTL1HDAC6 | |
| SCHEMBL6716858 | 0.74 | MLYCD (0.54) | MLYCDNAAAPPARGL3MBTL1PLK1 | |
| SCHEMBL11338002 | 0.74 | MLYCD (0.63) | MLYCDNAAAEPHX2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |