Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044174 | 0.86 | MLYCD (0.58) | MLYCDNAAAL3MBTL1EPHX2SMN1; SMN2 | |
| SCHEMBL6022530 | 0.82 | MLYCD (0.58) | MLYCDNAAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL1854718 | 0.81 | MLYCD (0.49) | MLYCDNAAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL6718534 | 0.80 | NAAA (0.73) | MLYCDNAAAL3MBTL1MEN1KMT2A | |
| SCHEMBL5044259 | 0.79 | NAAA (0.62) | MLYCDNAAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL6726138 | 0.78 | MLYCD (0.56) | MLYCDNAAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL6022200 | 0.78 | DRD2 (0.49) | MLYCDNAAAL3MBTL1SMN1; SMN2CA2 | |
| SCHEMBL6717480 | 0.78 | MLYCD (0.53) | MLYCDNAAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL5039488 | 0.77 | MLYCD (0.49) | MLYCDNAAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL11338002 | 0.77 | MLYCD (0.63) | MLYCDNAAAL3MBTL1EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |
| EP-1732534-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | Applied Research Systems ARS Holding N.V. (AN) | 2006-12-20 | — | — | EP | claimed |
| WO-2005082347-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | APLLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-09-09 | — | — | WO | claimed |
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | disclosed |