Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044173 | 0.86 | MLYCD (0.54) | MLYCDL3MBTL1NAAAHDAC3HDAC1 | |
| SCHEMBL1853826 | 0.85 | MLYCD (0.64) | MLYCDL3MBTL1NAAAHDAC3HDAC1 | |
| SCHEMBL1854718 | 0.84 | MLYCD (0.49) | MLYCDL3MBTL1NAAAHDAC3MEN1 | |
| SCHEMBL1852697 | 0.83 | MLYCD (0.58) | MLYCDL3MBTL1NAAAHDAC3HDAC1 | |
| SCHEMBL5044057 | 0.83 | EPHX2 (0.55) | MLYCDL3MBTL1NAAAHDAC3HDAC1 | |
| SCHEMBL5044022 | 0.80 | MRGPRX4 (0.56) | MLYCDNAAAHDAC3HDAC1HDAC2 | |
| SCHEMBL6718748 | 0.79 | MLYCD (0.58) | MLYCDL3MBTL1NAAAHDAC3HDAC1 | |
| SCHEMBL6716860 | 0.79 | MLYCD (0.58) | MLYCDL3MBTL1NAAAHDAC3HDAC1 | |
| SCHEMBL27619607 | 0.79 | NAAA (0.58) | MLYCDL3MBTL1NAAAHDAC3HDAC1 | |
| SCHEMBL5044262 | 0.79 | L3MBTL1 (0.62) | MLYCDL3MBTL1NAAAHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | disclosed |