Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.41 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.41 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044219 | 0.90 | MLYCD (0.48) | MLYCDHDAC1HDAC3TRPV1HPGD | |
| SCHEMBL5045263 | 0.89 | MAPK14 (0.48) | MAPK14MLYCDROCK2NAMPTROCK1 | |
| SCHEMBL5044055 | 0.86 | MLYCD (0.51) | MAPK14MLYCDNAMPTDDR1HDAC1 | |
| SCHEMBL4323998 | 0.85 | NAMPT (0.43) | MAPK14MLYCDROCK2NAMPTROCK1 | |
| SCHEMBL27619621 | 0.81 | NAAA (0.48) | MAPK14HDAC1HDAC3LMNAHPGD | |
| SCHEMBL5048873 | 0.81 | MLYCD (0.54) | MLYCDNAMPTHDAC1HDAC3HPGD | |
| SCHEMBL5044228 | 0.81 | NAMPT (0.46) | MLYCDNAMPTDDR1HDAC1HDAC3 | |
| SCHEMBL5044609 | 0.80 | EPHX2 (0.52) | NAMPTHDAC1HDAC3TRPV1HPGD | |
| SCHEMBL6022083 | 0.80 | TRPV1 (0.48) | MLYCDNAMPTHDAC1HDAC3TRPV1 | |
| SCHEMBL5045260 | 0.80 | NAMPT (0.46) | MAPK14MLYCDROCK2NAMPTROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |