Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044232 | 0.90 | MAPK14 (0.49) | MLYCDHPGDHDAC3HDAC1TRPV1 | |
| SCHEMBL5044609 | 0.90 | EPHX2 (0.52) | EPHX2NR1H4ALDH1A1HPGDKDM4E | |
| SCHEMBL5048873 | 0.87 | MLYCD (0.54) | MLYCDEPHX2ALDH1A1HPGDHDAC3 | |
| SCHEMBL6022083 | 0.86 | TRPV1 (0.48) | MLYCDEPHX2NR1H4ALDH1A1HPGD | |
| SCHEMBL27619621 | 0.86 | NAAA (0.48) | EPHX2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL28752190 | 0.84 | FOLH1 (0.47) | MLYCDHPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL1851709 | 0.84 | GCGR (0.48) | MLYCDEPHX2NR1H4ALDH1A1HPGD | |
| SCHEMBL5044218 | 0.81 | MLYCD (0.47) | MLYCDEPHX2ALDH1A1HPGDKDM4E | |
| SCHEMBL5044055 | 0.81 | MLYCD (0.51) | MLYCDALDH1A1CYP2C19CYP3A4HDAC3 | |
| SCHEMBL24119885 | 0.80 | MLYCD (0.68) | MLYCDEPHX2NR1H4ALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |