Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 4/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777743 | 0.73 | KDM4E (0.66) | IDO1KDM4EMAPTDAOHPGD | |
| SCHEMBL3700465 | 0.73 | KDM4E (0.66) | IDO1KDM4EMAPTDAOHPGD | |
| SCHEMBL28208771 | 0.73 | KDM4E (0.55) | KDM4EHPGDHSD17B10CHEK2FLT3 | |
| SCHEMBL29362757 | 0.72 | FLT3 (0.71) | IDO1KDM4EMAPTDAOHPGD | |
| SCHEMBL118686 | 0.72 | FLT3 (0.71) | IDO1KDM4EMAPTDAOHPGD | |
| SCHEMBL4664560 | 0.72 | IKBKB (0.62) | DHODHIKBKBCHUKPARP1 | |
| SCHEMBL10084366 | 0.71 | IDO1 (0.54) | IDO1KDM4EMAPTDAOHPGD | |
| Bromide SCHEMBL6056708 | 0.71 | FLT3 (0.69) | IDO1KDM4EMAPTDAOHPGD | |
| Water SCHEMBL30277651 | 0.71 | FLT3 (0.69) | IDO1KDM4EMAPTDAOHPGD | |
| Hydrochloric Acid SCHEMBL20569802 | 0.71 | FLT3 (0.69) | IDO1KDM4EMAPTDAOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959737-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007076286-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |