SCHEMBL50448

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14235103	0.86	NGFR (0.48)	IDO1TDO2GPR35MEN1HPGD
	SCHEMBL51829	0.81	MEN1 (0.51)	GPR35MEN1HPGDKMT2AKDM4E
	SCHEMBL13652078	0.81	ADRA2A (0.36)	IDO1TDO2GPR35MEN1HPGD
	SCHEMBL11883433	0.75	GPR35 (0.61)	GPR35MEN1HPGDKMT2AKDM4E
	SCHEMBL29974758	0.74	IDO1 (0.75)	IDO1TDO2GPR35MEN1HPGD
	SCHEMBL22747188	0.74	IDO1 (0.75)	IDO1TDO2GPR35MEN1HPGD
	SCHEMBL52094	0.71	HPGD (0.58)	GPR35MEN1HPGDKMT2AKDM4E
	SCHEMBL51286	0.71	ALOX15 (0.41)	MEN1HPGDKMT2AKDM4EALOX15
	SCHEMBL9452298	0.70	HPGD (0.57)	GPR35MEN1HPGDKMT2AKDM4E
	SCHEMBL51080	0.69	GLA (0.59)	IDO1TDO2GPR35HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.