Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670156 | 0.92 | PTPN11 (0.45) | FFAR1PTGESPTGDR2RORCFFAR4 | |
| SCHEMBL5044116 | 0.91 | FFAR1 (0.43) | FFAR1PSMB5RORC | |
| SCHEMBL4671672 | 0.85 | FFAR1 (0.38) | FFAR1PTGESPTGDR2PSMB5RORC | |
| SCHEMBL5045341 | 0.84 | PPARA (0.44) | ACACB | |
| SCHEMBL1854444 | 0.83 | PTGES (0.48) | FFAR1PTGESPTGDR2PSMB5ACACB | |
| SCHEMBL4672605 | 0.83 | FFAR1 (0.56) | FFAR1PTGESPTGDR2RORCFFAR4 | |
| SCHEMBL2475473 | 0.81 | LSS (0.48) | FFAR1 | |
| SCHEMBL9185806 | 0.81 | TAAR1 (0.50) | FFAR1PTGDR2PSMB5ACACB | |
| SCHEMBL5048701 | 0.79 | S1PR4 (0.49) | PTGES | |
| SCHEMBL31035881 | 0.79 | LSS (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |