Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045341 | 0.91 | PPARA (0.44) | S1PR4S1PR1S1PR3S1PR5PPARA | |
| SCHEMBL5044116 | 0.84 | FFAR1 (0.43) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL1859862 | 0.84 | PTGES (0.50) | S1PR4S1PR1S1PR3S1PR5PPARA | |
| SCHEMBL4316069 | 0.83 | PTGES (0.49) | S1PR4S1PR1S1PR3S1PR5PPARA | |
| SCHEMBL4670156 | 0.83 | PTPN11 (0.45) | PTGES | |
| SCHEMBL1856325 | 0.80 | TP53 (0.48) | S1PR1S1PR3S1PR5PPARGPTGES | |
| SCHEMBL5045150 | 0.79 | FFAR1 (0.47) | PTGES | |
| SCHEMBL2475473 | 0.78 | LSS (0.48) | MEN1KMT2APSEN1 | |
| SCHEMBL4672605 | 0.77 | FFAR1 (0.56) | PTGES | |
| SCHEMBL1851802 | 0.76 | PTGES (0.44) | S1PR1S1PR5PPARGPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | disclosed |