Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045150 | 0.91 | FFAR1 (0.47) | FFAR1PSMB5RORC | |
| SCHEMBL2475473 | 0.87 | LSS (0.48) | FFAR1LSSMTORMEN1KMT2A | |
| SCHEMBL5048701 | 0.84 | S1PR4 (0.49) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL31035881 | 0.84 | LSS (0.45) | LSSMTORMEN1KMT2A | |
| SCHEMBL4670156 | 0.83 | PTPN11 (0.45) | FFAR1RORCHDAC1HDAC8 | |
| SCHEMBL4327886 | 0.81 | MEN1 (0.43) | FFAR1PSMB5LSSMTORMEN1 | |
| SCHEMBL9408547 | 0.80 | TDP1 (0.47) | FFAR1RORCLSSMTORMEN1 | |
| SCHEMBL27659345 | 0.78 | L3MBTL1 (0.43) | FFAR1KMT2AL3MBTL1HDAC1HDAC8 | |
| SCHEMBL5047241 | 0.77 | TMEM97 (0.56) | LSSMEN1KMT2AL3MBTL1MCHR1 | |
| SCHEMBL18586316 | 0.77 | SORT1 (0.43) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |