Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048701 | 0.91 | S1PR4 (0.49) | PPARAPPARGPLA2G4BS1PR4S1PR1 | |
| SCHEMBL4670156 | 0.88 | PTPN11 (0.45) | — | |
| SCHEMBL1851802 | 0.85 | PTGES (0.44) | PPARGACACBS1PR1S1PR5 | |
| SCHEMBL5045150 | 0.84 | FFAR1 (0.47) | ACACB | |
| SCHEMBL1853816 | 0.84 | PTGES (0.43) | PPARGPLA2G4BACACBS1PR1S1PR3 | |
| SCHEMBL4672605 | 0.84 | FFAR1 (0.56) | — | |
| SCHEMBL1855304 | 0.81 | ACACB (0.42) | ACACB | |
| SCHEMBL1855943 | 0.80 | ACACB (0.42) | PLA2G4BACACB | |
| SCHEMBL1851797 | 0.79 | ALOX5 (0.43) | PPARAPPARGPLA2G4BACACBS1PR4 | |
| SCHEMBL1855944 | 0.78 | ACACB (0.40) | PPARAPPARGPLA2G4BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |