Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462928 | 0.91 | FDPS (0.51) | FDPSALDH1A1MAPK1TUBB4ATUBB | |
| SCHEMBL7462173 | 0.86 | FDPS (0.50) | FDPSALDH1A1MAPK1TSHRMEN1 | |
| SCHEMBL7829405 | 0.84 | FDPS (0.49) | FDPSALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL9122728 | 0.84 | FDPS (0.49) | FDPSALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8772656 | 0.84 | FDPS (0.49) | FDPSALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL4007449 | 0.84 | ALDH1A1 (0.51) | FDPSALDH1A1MAPK1TUBB4ATUBB | |
| SCHEMBL18033266 | 0.84 | FDPS (0.45) | FDPSALDH1A1MAPK1TUBB4ATUBB | |
| SCHEMBL11765947 | 0.84 | ALDH1A1 (0.63) | FDPSALDH1A1MAPK1TUBB4ATUBB | |
| SCHEMBL14224314 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL7466433 | 0.82 | FDPS (0.53) | FDPSALDH1A1MAPK1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062905-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062901-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |