Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14195847 | 0.94 | S1PR2 (0.53) | ALDH1A1L3MBTL1MAPTKMT2AHPGD | |
| SCHEMBL13221149 | 0.93 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPTKMT2AHPGD | |
| SCHEMBL5712342 | 0.90 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTKMT2AHPGD | |
| SCHEMBL7462928 | 0.89 | FDPS (0.51) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL15771884 | 0.85 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTKMT2AHPGD | |
| SCHEMBL2650454 | 0.85 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MAPTKMT2AHPGD | |
| SCHEMBL5712326 | 0.85 | S1PR2 (0.46) | ALDH1A1L3MBTL1MAPTKMT2AHPGD | |
| SCHEMBL7462173 | 0.84 | FDPS (0.50) | ALDH1A1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL5045277 | 0.84 | FDPS (0.46) | ALDH1A1L3MBTL1MAPTKMT2AHPGD | |
| SCHEMBL9122728 | 0.83 | FDPS (0.49) | ALDH1A1KMT2AMEN1MAPK1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383736-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| US-6967220-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2005-11-22 | — | — | US | disclosed |
| US-20040106795-A1 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106795-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | ALDH1A1 4367/4885L3MBTL1 1436/4885MAPT 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.