Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044417 | 0.88 | FFAR1 (0.47) | FFAR1FFAR4SLC6A4HRH3ACACB | |
| SCHEMBL5047701 | 0.88 | FFAR1 (0.47) | FFAR1FFAR4SLC6A4HRH3ACACB | |
| SCHEMBL5046558 | 0.88 | FFAR1 (0.47) | FFAR1FFAR4SLC6A4HRH3ACACB | |
| SCHEMBL5044888 | 0.83 | ITGB1 (0.45) | FFAR1FFAR4ACACBGABRPGABRD | |
| SCHEMBL2945555 | 0.82 | GABRP (0.43) | FFAR1FFAR4SLC6A4HRH3GABRP | |
| SCHEMBL5048882 | 0.81 | HRH3 (0.37) | SLC6A4HRH3KDM4EALDH1A1 | |
| SCHEMBL1850254 | 0.79 | GABRP (0.38) | FFAR1FFAR4GABRPGABRDGABRA1 | |
| SCHEMBL2946865 | 0.78 | GABRP (0.47) | FFAR1FFAR4SLC6A4HRH3GABRP | |
| SCHEMBL1851060 | 0.75 | FFAR1 (0.37) | FFAR1FFAR4ACACBPPARGPPARD | |
| SCHEMBL1855218 | 0.73 | PTGES (0.41) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |