SCHEMBL5046029

SCHEMBL5046029

CNC(=O)N(C)c1ccc(C)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
GPBAR1 Q8TDU6 1/20 0.44
ROCK2 O75116 1/20 0.42
CHRNA1 P02708 1/20 0.40
CHRNG P07510 1/20 0.40
CHRNB1 P11230 1/20 0.40
CHRNB2 P17787 1/20 0.40
SLC6A2 P23975 1/20 0.40
CHRNB4 P30926 1/20 0.40
SLC6A4 P31645 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CHRND Q07001 1/20 0.40
ALDH1A1 P00352 3/20 0.40
KCNJ6 P48051 1/20 0.40
KCNJ5 P48544 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28567911 0.87 GPBAR1 (0.45) SMN1; SMN2CYP3A4CYP2C19GPBAR1ROCK2
SCHEMBL30047589 0.86 APEX1 (0.49) RAB9ASMN1; SMN2CYP3A4GPBAR1ROCK2
SCHEMBL7052343 0.86 APEX1 (0.49) RAB9ASMN1; SMN2CYP3A4GPBAR1ROCK2
SCHEMBL11542956 0.82 RAB9A (0.45) RAB9ASMN1; SMN2CYP3A4CYP2C19GPBAR1
SCHEMBL534366 0.81 ROCK2 (0.43) RAB9ASMN1; SMN2CYP3A4ROCK2ALDH1A1
SCHEMBL11006800 0.81 SMN1; SMN2 (0.53) RAB9ASMN1; SMN2CYP3A4CYP2C19GPBAR1
SCHEMBL9143132 0.80 ALDH1A1 (0.49) RAB9ASMN1; SMN2ROCK2ALDH1A1NPC1
SCHEMBL10940226 0.79 SMN1; SMN2 (0.48) RAB9ASMN1; SMN2CYP3A4CYP2C19GPBAR1
SCHEMBL27257123 0.78 ROCK2 (0.39) RAB9AROCK2SLC6A2SLC6A4SLC6A3
SCHEMBL9408595 0.78 ROCK2 (0.59) RAB9ASMN1; SMN2CYP3A4ROCK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461969-A Method for producing a laminated core, laminated core and electric machine 蒂森克虏伯钢铁欧洲股份公司 2022-12-09 CN claimed
CN-113748586-A Sheet material for producing electromagnetic components, in particular stator cores or rotor cores, and method for producing electromagnetic components 蒂森克虏伯钢铁欧洲股份公司 2021-12-03 CN claimed
EP-0149099-A2 Synergistic herbicidal compositions STAUFFER CHEMICAL COMPANY (US) 1985-07-24 EP claimed
US-11820922-B2 Adhesive composition DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US) 2023-11-21 US disclosed
EP-3697862-B1 ADHESIVE COMPOSITION DDP SPECIALTY ELECTRONIC MAT US INC (US) 2023-05-03 EP disclosed
CN-115461969-A Method for producing a laminated core, laminated core and electric machine 蒂森克虏伯钢铁欧洲股份公司 2022-12-09 CN disclosed
CN-111542579-B Adhesive composition DDP特种电子材料美国公司 2022-10-21 CN disclosed
CN-112384489-A Method for producing organic compound 尤尼吉可株式会社 2021-02-19 CN disclosed
CN-107129665-B Curable resin composition 东京应化工业株式会社 2020-11-24 CN disclosed
EP-3697862-A1 ADHESIVE COMPOSITION DDP Specialty Electronic Materials US, Inc. (US) 2020-08-26 EP disclosed
US-20200231849-A1 ADHESIVE COMPOSITION DDP SPECIALTY ELECTRONICS MATERIALS US, INC. (US) 2020-07-23 US disclosed
US-5032488-A Method of metalizing a surface using a mixture of olefin and dibenzalacetone palladium complex CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
CN-1050020-A The dihydropyridine compound that replaces MONSANTO CO (US) 1991-03-20 CN disclosed
US-4992488-A Commutator CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
US-4952645-A ADHESIVES; LOW TEMPERATURE FLEXIBILITY, CORROSION RESISTANCE CIBA-GEIGY CORPORATION (US) 1990-08-28 US disclosed
EP-0371947-A1 Substituted pyrazoles and their use as herbicides Monsanto Company (US) 1990-06-06 EP disclosed
US-4908273-A Adducts I and II containing epoxide groups, carboxyl-terminated butadiene-acrylonitrile rubber or polyester adduct, aromatic di- or polyglycidyl ether, second similar curable layer, additives CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed
US-4826927-A LAMINATING RESINS, ELECTRO-RESINS CIBA-GEIGY CORPORATION (US) 1989-05-02 US disclosed
EP-0302983-A2 Synergistically acting selective herbicidal agent for cereal crops CIBA-GEIGY AG (CH) 1989-02-15 EP disclosed
EP-0149099-A2 Synergistic herbicidal compositions STAUFFER CHEMICAL COMPANY (US) 1985-07-24 EP disclosed