SCHEMBL5046289

SCHEMBL5046289

C=COC(COCCO)OCC

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5045887 0.97 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL4913690 0.85 HSD17B10 (0.38)
SCHEMBL16149960 0.83 THRB (0.31)
SCHEMBL8865873 0.82 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL896451 0.82
SCHEMBL5045895 0.81 TSHR (0.33) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL4910614 0.79
SCHEMBL28597541 0.79 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL27167532 0.79 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL7532204 0.79 MEN1 (0.39) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1553113-B1 BIOCOMPATIBLE POLYMER AND FILTER FOR SELECTIVELY ELIMINATING LEUCOCYTES USING THE SAME ASAHI KASEI KURARAY MEDICAL CO (JP) 2008-11-19 EP disclosed
US-7439013-B2 Biocompatible polymer and filter for selectively eliminating leucocytes using the same ASAHI KASEI KURARAY MEDICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20060073467-A1 Biocompatible polymer and filter for selectively eliminating leucocytes using the same ASAHI KASEI MEDICAL CO., LTD. (JP) 2006-04-06 US disclosed
EP-1553113-A1 BIOCOMPATIBLE POLYMER AND FILTER FOR SELECTIVELY ELIMINATING LEUCOCYTES USING THE SAME ASAHI MEDICAL Co., Ltd. (JP) 2005-07-13 EP disclosed
EP-0781809-B1 Resin composition for sealing liquid crystal cells MITSUI CHEMICALS INC (JP) 2000-08-02 EP disclosed
US-5908899-A RUBBER-MODIFIED UNSATURATED COMPOUND OBTAINED BY GRAFTING A MONOMER HAVING AT LEAST ONE POLYMERIZABLE ETHYLENICALLY UNSATURATED BOND IN A MOLECULE WITH AT LEAST ONE RUBBER; A COUPLING AGENT, A FILLER AND A PHOTOPOLYMERIZATION INITIATOR. MITSUI CHEMICALS, INC. (JP) 1999-06-01 US disclosed
EP-0781809-A2 Resin composition for sealing liquid crystal cells MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-02 EP disclosed