Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17642582 | 0.83 | AKR1C3 (0.51) | L3MBTL3L3MBTL1GRIN2BKMT2AHRH3 | |
| SCHEMBL12082440 | 0.83 | AKR1C3 (0.51) | L3MBTL3L3MBTL1GRIN2BKMT2AHRH3 | |
| SCHEMBL16195572 | 0.83 | MAPT (0.50) | L3MBTL3L3MBTL1GRIN2BKMT2AHRH3 | |
| SCHEMBL17660589 | 0.79 | L3MBTL1 (0.48) | L3MBTL3L3MBTL1GRIN2BKMT2AMEN1 | |
| SCHEMBL16440176 | 0.79 | HSD11B1 (0.51) | L3MBTL3L3MBTL1GRIN2BKMT2AHRH3 | |
| SCHEMBL664774 | 0.77 | LMNA (0.58) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL16195539 | 0.76 | KMT2A (0.72) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL95920 | 0.75 | L3MBTL3 (0.62) | L3MBTL3L3MBTL1HRH3MBTD1ALDH1A1 | |
| SCHEMBL4334818 | 0.75 | GRIN2B (0.57) | L3MBTL3L3MBTL1GRIN2BMBTD1ALDH1A1 | |
| SCHEMBL23160621 | 0.74 | AOC3 (0.55) | L3MBTL3L3MBTL1GRIN2BMBTD1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976841-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Neuromed Pharmaceuticals, Ltd. (CA) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007071035-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2007-06-28 | — | — | WO | disclosed |