Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048124 | 0.92 | MAP3K5 (0.40) | SMN1; SMN2MAPTMAP3K5CCNE1CDK2 | |
| SCHEMBL5051783 | 0.90 | MAP3K5 (0.40) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL5048107 | 0.82 | ACHE (0.38) | SMN1; SMN2MAPTCCNE1CDK2ACHE | |
| SCHEMBL5045348 | 0.82 | ACHE (0.37) | MAPTCCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL7617736 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL9079905 | 0.77 | MEN1 (0.42) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL7843904 | 0.74 | SCD (0.43) | SMN1; SMN2ACHESCDNPC1RAB9A | |
| SCHEMBL14477481 | 0.72 | RAB9A (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1CCNE2 | |
| SCHEMBL6269147 | 0.69 | CDK2 (0.42) | SMN1; SMN2MAP3K5CCNA2CCNE1CDK2 | |
| SCHEMBL9079453 | 0.68 | BCHE (0.37) | KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873156-A1 | Process for the preparation of 6-[[(alkoxy)carbonyl]amino]-9H-Purine-9-acetic acid and 4-[(alkoxycarbonyl)amino]-2-oxo-1(2H)-Pyrimidineacetic acid derivatives as synthons for the synthesis of peptide nucleic acids | PerSeptive Biosystems, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-0736027-B1 | GUANINE SYNTHONS FOR PEPTIDE NUCLEIC ACID SYNTHESIS AND METHOD FOR PRODUCTION | PERSEPTIVE BIOSYSTEMS INC (US) | 2002-05-29 | — | — | EP | disclosed |