Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446096 | 0.75 | DAPK3 (0.41) | ALDH1A1GAADAPK3JAK2PRKD3 | |
| SCHEMBL4247977 | 0.74 | ABL1 (0.40) | ALDH1A1GAADAPK3JAK2PRKD3 | |
| SCHEMBL13731286 | 0.74 | DAPK3 (0.40) | ALDH1A1DAPK3JAK2PRKD3MAP4K4 | |
| Hydrochloric Acid SCHEMBL1396143 | 0.72 | ABL1 (0.39) | ALDH1A1GAADAPK3JAK2PRKD3 | |
| SCHEMBL20101952 | 0.71 | ALDH1A1 (0.40) | ALDH1A1GAADAPK3JAK2PRKD3 | |
| Ethane SCHEMBL15559374 | 0.71 | ABL1 (0.38) | ALDH1A1GAADAPK3JAK2PRKD3 | |
| SCHEMBL31294085 | 0.70 | NOTUM (0.43) | ALDH1A1GAADAPK3JAK2PRKD3 | |
| SCHEMBL3938677 | 0.69 | KDM4E (0.45) | ALDH1A1GAAKDM4EMAPTRXFP1 | |
| SCHEMBL16007133 | 0.69 | ALDH1A1 (0.47) | ALDH1A1GAADAPK3JAK2PRKD3 | |
| SCHEMBL26301302 | 0.68 | DAPK3 (0.35) | ALDH1A1GAADAPK3JAK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966215-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | Novartis AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |